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Our top choices for Upstate South Carolina hotels

Best Western Travelers Rest Greenville

Best Western Travelers Rest Greenville
2.5 star property
Travelers Rest
7.6 out of 10, Good, (1,004 reviews)
"It was a pretty room. I only needed 1 night while visiting my son in the hospital. The employees were kind. The breakfast was decent. The bed and pillows felt amazing and the shower got nice and hot."
United States
Molly
The price is AU$124
includes taxes & fees
2 Mar - 3 Mar
Best Western Travelers Rest Greenville

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (2 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
The price is AU$264
includes taxes & fees
5 Mar - 6 Mar
Carolina Camp Cedar

The Night Inn

The Night Inn
2.5 star property
Union
7.8 out of 10, Good, (84 reviews)
"Check in was easy and staff member pleasant. Room extremely clean. Beds were comfortable. Great value for price. "
United States
April
The price is AU$107
includes taxes & fees
2 Mar - 3 Mar
The Night Inn

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel
3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (722 reviews)
"The staff were all very pleasant. "
United States
michelle
The price is AU$161
includes taxes & fees
22 Mar - 23 Mar
Inn on the Square, an Ascend Collection Hotel

Holiday Inn Express & Suites Greenwood Mall by IHG

Holiday Inn Express & Suites Greenwood Mall by IHG
2.5 star property
Greenwood
9.0 out of 10, Wonderful, (493 reviews)
"Very clean room and friendly staff"
United States
Mark
The price is AU$198
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express & Suites Greenwood Mall by IHG

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.2 out of 10, Very good, (1,003 reviews)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson

Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26
2.5 star property
Clinton
7.4 out of 10, Good, (530 reviews)
"Super clean and quiet and staff was extremely nice and friendly"
United States
Kimberly
The price is AU$103
includes taxes & fees
1 Apr - 2 Apr
Quality Inn Clinton - Laurens I-26

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (801 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
The price is AU$232
includes taxes & fees
2 Mar - 3 Mar
The Inn at Patrick Square

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (978 reviews)
"Everything was very nice "
United States
Paige
The price is AU$232
includes taxes & fees
2 Mar - 3 Mar
Clemson University's James F. Martin Inn

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (567 reviews)
"Great stay"
United States
Megan
The Abernathy of Clemson

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very good, (1,001 reviews)
"Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! "
United States
Delaney
The price is AU$151
includes taxes & fees
8 Mar - 9 Mar
Comfort Inn & Suites Clemson - University Area

Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC
2.5 star property
Greer
9.6 out of 10, Exceptional, (434 reviews)
"Parking garage for hotel guests, location was great, hotel was clean, staff was great. "
United States
Tyler
The price is AU$244
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn Greer Greenville, SC

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville
2.5 star property
Greer
8.6 out of 10, Excellent, (763 reviews)
"this is the best hotel friendly clean rooms, quiet and the staff is great."
United States
pamela
The price is AU$139
includes taxes & fees
8 Mar - 9 Mar
Comfort Inn & Suites Greer - Greenville

Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport
2.5 star property
Greenville
8.4 out of 10, Very good, (340 reviews)
"everything was perfect "
United States
Makiya
The price is AU$122
includes taxes & fees
2 Mar - 3 Mar
Woodspring Suites Greenville Airport

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (958 reviews)
"Nice facility "
United States
Rishandrea
The price is AU$192
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express & Suites Clemson by IHG

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (455 reviews)
"Friendly staff, clean rooms, excellent food! "
United States
Ashley
The price is AU$158
includes taxes & fees
8 Mar - 9 Mar
Four Points by Sheraton Spartanburg

Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
2.5 star property
Spartanburg
8.2 out of 10, Very good, (1,000 reviews)
"Easy to get in and out"
United States
Thomas
The price is AU$141
includes taxes & fees
8 Mar - 9 Mar
Comfort Suites At WestGate Mall

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1,006 reviews)
"Our room was very clean and the staff were very nice and courteous!"
United States
Tina
The price is AU$142
includes taxes & fees
5 Mar - 6 Mar
Best Western Plus Clemson Hotel & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1,085 reviews)
"Great staff, awesome property"
United States
Annisha
The price is AU$179
includes taxes & fees
15 Mar - 16 Mar
Embassy Suites Greenville Golf Resort & Conference Center

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (763 reviews)
"Awesome hotel and very convenient for visiting Clemson."
United States
Nina
The price is AU$388
includes taxes & fees
3 Mar - 4 Mar
The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Southeastern United States attractions

Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

It is only a 1 mile hike to this beauty.  View a video about it here:  https://www.hdcarolina.com/episode/riley-moore-falls

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Photo by Ryan Watts
Open Photo by Ryan Watts

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